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The Guiding Principle of Chiral Innovative drugs clearly stipulates that "the direct method for determination of molecular configuration of chiral drugs is single crystal X-ray structure analysis".
X-ray diffraction is an important means for people to understand and explore nature, especially in condensed matter physics, life medicine, history and many other fields play an active role.
Unlike powder XRD, which is widely used in the late stage of drug development and production, single crystal X-ray diffraction technology plays an important role in the early and middle stages of drug development.
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With the gradual increase of drug crystal regulation, the quantitative analysis of the effective crystal in drug preparations is a very important link in the quality control process of drug production.
XRD technology is widely used in the fields of crystallography, physics and metallurgy, including qualitative and quantitative, crystal structure, mechanical analysis, etc. This paper mainly lists its application in polymer research.
The application of XRD in the refractory industry involves all aspects of refractory production. From raw material quality inspection, production process control to product quality inspection.
In drug research and development, crystal research runs through all stages from the screening of lead compounds to the final drug marketing.
Petrological studies often require the identification of mineral compositions in rocks, especially those that are less abundant. Therefore, the qualitative analysis of minerals is the most important application of X-ray diffraction in the study of mineral petrology.