Crystal type and crystal fetish
2024-02-18 10:00Crystal form
Substances in crystallization due to the influence of various factors, so that the intramolecular or intermolecular bonding mode changes, resulting in molecules or atoms in the lattice space arrangement is different, forming different crystal structures.
Crystal habit
Refers to the appearance of the crystal shape
Crystal type & Crystal fetish
1. Crystal fetish is the appearance of crystal shape.
2. The same crystalline substance can have a variety of different shapes of crystals, such as common needle crystals, sheet crystals, columnar crystals, etc. The crystal type D2 PHASER cannot be determined based on the crystal shape.
3. The difference between crystal fests is the difference in macro appearance, which can be observed with ordinary light microscopy or the naked eye. To determine the difference in crystal type, thermal analysis, X-ray diffractometer and other tools are required.
4. Crystal is of great significance to ensure the quality of drugs; The effect on curative effect is not as great as that of polycrystalline form.
5. Crystal fetish directly affects the quality of the tablet.
6. Influencing factors of crystal fester: temperature, supersaturation concentration, impurities, viscosity, pressure, crystallization rate, etc.