The cabinet X-ray irradiator system generates high-energy X-rays to irradiate cells or small animals. Used for various basic and applied research. In history, radioactive isotope irradiator equipment has been used, which requires transporting samples to a core irradiation facility. Today, smaller, safer, simpler, and lower cost X-ray irradiator devices can be installed in laboratories for convenient and rapid irradiator of cells. Various samples can be directly irradiated in the laboratory without affecting fertility or safety. This biological X-ray irradiator device is convenient for personnel without professional X-ray training to use, and there are no expensive license applications or maintenance costs for safety or radiation sources. The X-ray irradiator instrument is easy to operate, safe, reliable, and cost-effective, and can replace radioactive isotope sources.